" /> protein tyrosine phosphatase, Non-Receptor type 12 - CISMeF





Preferred Label : protein tyrosine phosphatase, Non-Receptor type 12;

MeSH definition : A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of a N-terminal catalytic domain and a large C-terminal domain that is enriched in PROLINE, GLUTAMIC ACID, SERINE, and THREONINE residues (PEST sequences). The phosphatase subtype is ubiquitously expressed and implicated in the regulation of a variety of biological processes such as CELL MOVEMENT; CYTOKINESIS; focal adhesion disassembly; and LYMPHOCYTE ACTIVATION.;

MeSH synonym : ptpase, pep; ptp-pest; PEST-Enriched Phosphatase; pest enriched phosphatase; phosphatase, pest-enriched; pep protein tyrosine phosphatase; PEP PTPase; protein tyrosine phosphatase, non receptor type 12;

Registry Number MeSH : EC 3.1.3.48;

Is substance : O;

UNII : EC 3.1.3.48;

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A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of a N-terminal catalytic domain and a large C-terminal domain that is enriched in PROLINE, GLUTAMIC ACID, SERINE, and THREONINE residues (PEST sequences). The phosphatase subtype is ubiquitously expressed and implicated in the regulation of a variety of biological processes such as CELL MOVEMENT; CYTOKINESIS; focal adhesion disassembly; and LYMPHOCYTE ACTIVATION.

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30/07/2025


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