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Preferred Label : perforin;

MeSH definition : A calcium-dependent pore-forming protein synthesized in cytolytic LYMPHOCYTES and sequestered in secretory granules. Upon immunological reaction between a cytolytic lymphocyte and a target cell, perforin is released at the plasma membrane and polymerizes into transmembrane tubules (forming pores) which lead to death of a target cell.;

MeSH synonym : lymphocyte pore forming protein; lymphocyte pore-forming protein; perforin 1; pore-forming protein, lymphocyte; cytolysin;

Registry Number MeSH : 126465-35-8;

Wikipedia link : https://en.wikipedia.org/wiki/Perforin;

Is substance : O;

Détails


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A calcium-dependent pore-forming protein synthesized in cytolytic LYMPHOCYTES and sequestered in secretory granules. Upon immunological reaction between a cytolytic lymphocyte and a target cell, perforin is released at the plasma membrane and polymerizes into transmembrane tubules (forming pores) which lead to death of a target cell.

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27/07/2025


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