Interleukin-1 Receptor-Associated kinases

Preferred Label : Interleukin-1 Receptor-Associated kinases;

MeSH definition : A family of intracellular signaling kinases that were identified by their ability to signal from the activated INTERLEUKIN-1 RECEPTORS. Signaling from these kinases involves their interaction with SIGNAL TRANSDUCING ADAPTOR PROTEINS such as MYELOID DIFFERENTIATION FACTOR 88 and TNF RECEPTOR-ASSOCIATED FACTOR 6.;

MeSH synonym : kinase, il-1 receptor-associated; il-1 receptor-associated kinase; irak kinases; kinases, interleukin-1 receptor-associated; receptor-associated kinases, interleukin-1; kinases, irak; il 1 receptor associated kinase; receptor-associated kinase, il-1; interleukin-1 receptor-associated kinase; interleukin 1 receptor associated kinase; kinase, interleukin-1 receptor-associated; receptor-associated kinase, interleukin-1; interleukin 1 receptor associated kinases;

CISMeF synonym : EC 2.7.1.37;

MeSH hyponym : Interleukin-1 Receptor-Associated kinase 1; Interleukin-1 Receptor-Associated kinase 2; Interleukin-1 Receptor-Associated kinase 4; Interleukin-1 Receptor-Associated kinase 3; Interleukin 1 Receptor Associated Kinase 4; IRAK-4 Kinase; IRAK 4 Kinase; Kinase, IRAK-4; Interleukin 1 Receptor Associated Kinase 3; IRAK-3 Kinase; IRAK 3 Kinase; Kinase, IRAK-3; Interleukin 1 Receptor Associated Kinase 1; IRAK-1 Kinase; IRAK 1 Kinase; Kinase, IRAK-1; Interleukin 1 Receptor Associated Kinase 2; IRAK-2 Kinase; IRAK 2 Kinase; Kinase, IRAK-2;

MeSH Related Number : Interleukin-1 Receptor-Associated kinase 4; Interleukin-1 Receptor-Associated kinase 3; Interleukin-1 Receptor-Associated kinase 1; Interleukin-1 Receptor-Associated kinase 2; EC 2.7.11.1;

Registry Number MeSH : EC 2.7.11.1;

Related CAS MeSH : EC 2.7.11.1 (Interleukin-1 Receptor-Associated kinase 4); EC 2.7.11.1 (Interleukin-1 Receptor-Associated kinase 3); EC 2.7.11.1 (Interleukin-1 Receptor-Associated kinase 1); EC 2.7.11.1 (Interleukin-1 Receptor-Associated kinase 2);

Is substance : O;

UNII : EC 2.7.11.1;

Details

Origin ID

D053592;

UMLS CUI

C0387030;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- Interleukin-1 Receptor-Associated kinase 1 [MeSH concept]
- Interleukin-1 Receptor-Associated kinase 2 [MeSH concept]
- Interleukin-1 Receptor-Associated kinase 3 [MeSH concept]
- Interleukin-1 Receptor-Associated kinase 4 [MeSH concept]
- Interleukin-1 Receptor-Associated kinases [MeSH concept]
Related MeSH Supplementary Concept(s)
- IRAK1 protein, human [MeSH Supplementary Concept]
- IRAK1 protein, rat [MeSH Supplementary Concept]
- IRAK3 protein, human [MeSH Supplementary Concept]
- IRAK4 deficiency [MeSH Supplementary Concept]
- IRAK4 protein, human [MeSH Supplementary Concept]
- Irak1 protein, mouse [MeSH Supplementary Concept]
- Irak2 protein, mouse [MeSH Supplementary Concept]
- Irak3 protein, mouse [MeSH Supplementary Concept]
- Irak4 protein, mouse [MeSH Supplementary Concept]
- SSP protein, arabidopsis [MeSH Supplementary Concept]
- irak4 protein, zebrafish [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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