matrix metalloproteinase 14

Preferred Label : matrix metalloproteinase 14;

MeSH definition : A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the action of PROPROTEIN CONVERTASES such as FURIN. Matrix metalloproteinase 14 plays a direct role in the cleavage of proteins in the pericellular environment. In addition, it can function indirectly by enzymatically activating the proprotein form of MATRIX METALLOPROTEINASE 15.;

MeSH synonym : membrane type matrix metalloproteinase 1; metalloproteinase, mt1-matrix; mmp x1 protein; mmp 14 metalloproteinase; mmp14 metalloproteinase; metalloproteinase 14, matrix; Membrane-Type Matrix Metalloproteinase 1; mmp-14 metalloproteinase; metalloproteinase, mmp-14; mmp-x1 protein; MT-MMP-1; MT1-Matrix Metalloproteinase; mt1 matrix metalloproteinase; MT1-MMP; Membrane-Type 1 Matrix Metalloproteinase; membrane type 1 matrix metalloproteinase; metalloproteinase, mmp14;

Registry Number MeSH : EC 3.4.24.80;

Is substance : O;

UNII : EC 3.4.24.80;

Details

Origin ID

D053511;

UMLS CUI

C1618608;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Matrix Metalloproteinase-14 [NCIt concept]
Indexing information
- 2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-(4-methoxybenzyl)-1H-indol-3-yl)propanoic acid [MeSH Supplementary Concept]
Record concept(s)
- matrix metalloproteinase 14 [MeSH concept]
Related MeSH Supplementary Concept(s)
- MMP14 protein, human [MeSH Supplementary Concept]
- Mmp14 protein, mouse [MeSH Supplementary Concept]
- Mmp14 protein, rat [MeSH Supplementary Concept]
Related MeSH term(s)
- matrix metalloproteinase inhibitors [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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