MeSH definition : A NOD-signaling adaptor protein that contains a C-terminal leucine-rich domain which
recognizes bacterial PEPTIDOGLYCAN. It signals via an N-terminal caspase recruitment
domain that interacts with other CARD SIGNALING ADAPTOR PROTEINS such as RIP SERINE-THEONINE
KINASES. It plays a role in the host defense response by signaling the activation
of CASPASES and the MAP KINASE SIGNALING SYSTEM.;
A NOD-signaling adaptor protein that contains a C-terminal leucine-rich domain which
recognizes bacterial PEPTIDOGLYCAN. It signals via an N-terminal caspase recruitment
domain that interacts with other CARD SIGNALING ADAPTOR PROTEINS such as RIP SERINE-THEONINE
KINASES. It plays a role in the host defense response by signaling the activation
of CASPASES and the MAP KINASE SIGNALING SYSTEM.
Allowable qualifiers