MeSH definition : A widely expressed member of the TNF receptor-associated family that may play a role
in neuronal development and EMBRYOGENESIS. Although TNF receptor-associated factor
4 does not strongly associate with TUMOR NECROSIS FACTOR RECEPTORS it may be a signaling
partner with the GLUCOCORTICOID-INDUCED TNFR-RELATED PROTEIN that plays a role in
the activation of JNK MITOGEN-ACTIVATED PROTEIN KINASES and NF-KAPPA B.;
MeSH synonym : cysteine rich domain associated with ring and traf domains protein 1; tnf receptor associated protein 4; tnf receptor-associated protein 4; TRAF4; cysteine-rich domain associated with ring and traf domains protein 1; TNF receptor associated factor 4;
A widely expressed member of the TNF receptor-associated family that may play a role
in neuronal development and EMBRYOGENESIS. Although TNF receptor-associated factor
4 does not strongly associate with TUMOR NECROSIS FACTOR RECEPTORS it may be a signaling
partner with the GLUCOCORTICOID-INDUCED TNFR-RELATED PROTEIN that plays a role in
the activation of JNK MITOGEN-ACTIVATED PROTEIN KINASES and NF-KAPPA B.