MeSH definition : A death domain receptor signaling adaptor protein that plays a role in signaling the
activation of INITIATOR CASPASES such as CASPASE 2. It contains a death domain that
is specific for RIP SERINE-THEONINE KINASES and a caspase-binding domain that binds
to and activates CASPASES such as CASPASE 2.;
MeSH synonym : rip associated protein with a death domain; rip-associated protein with a death domain; Caspase and Rip Adaptor with Death Domain Protein; raidd signaling adaptor protein;
A death domain receptor signaling adaptor protein that plays a role in signaling the
activation of INITIATOR CASPASES such as CASPASE 2. It contains a death domain that
is specific for RIP SERINE-THEONINE KINASES and a caspase-binding domain that binds
to and activates CASPASES such as CASPASE 2.
Allowable qualifiers