PHEX phosphate regulating neutral endopeptidase

Preferred Label : PHEX phosphate regulating neutral endopeptidase;

MeSH definition : A membrane-bound metalloendopeptidase that may play a role in the degradation or activation of a variety of PEPTIDE HORMONES and INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS. Genetic mutations that result in loss of function of this protein are a cause of HYPOPHOSPHATEMIC RICKETS, X-LINKED DOMINANT.;

MeSH synonym : phosphate regulating endopeptidase homolog, x linked; phosphate regulating neutral endopeptidase; x linked phosphate regulating endopeptidase homolog; x-linked phosphate regulating endopeptidase homolog; PEX Phosphate Regulating Neutral Endopeptidase; phosphate regulating endopeptidase homolog, x-linked;

Registry Number MeSH : EC 3.4.24.-;

Is substance : O;

Details

Origin ID

D053402;

UMLS CUI

C1621912;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Disintegrin and Metalloproteinase Domain-Containing Protein 15 [NCIt concept]
- phosphate regulating endopeptidase X-linked [ORDO Gene]
- phosphate regulating endopeptidase X-linked [HGNC gene]
Record concept(s)
- PHEX phosphate regulating neutral endopeptidase [MeSH concept]
Related MeSH Supplementary Concept(s)
- PHEX protein, human [MeSH Supplementary Concept]
- phex protein, mouse [MeSH Supplementary Concept]
- phex protein, rat [MeSH Supplementary Concept]
Related MeSH term(s)
- familial hypophosphatemic rickets [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients