apolipoprotein c-iii

Preferred Label : apolipoprotein c-iii;

MeSH definition : A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS and CHYLOMICRON REMNANTS. Apo C-III, synthesized in the liver, is an inhibitor of LIPOPROTEIN LIPASE. Apo C-III modulates the binding of chylomicron remnants and VLDL to receptors (RECEPTORS, LDL) thus decreases the uptake of triglyceride-rich particles by the liver cells and subsequent degradation. The normal Apo C-III is glycosylated. There are several polymorphic forms with varying amounts of SIALIC ACID (Apo C-III-0, Apo C-III-1, and Apo C-III-2).;

MeSH synonym : Apo C-III; apo c iii; apolipoprotein ciii; apolipoprotein C III;

MeSH hyponym : apolipoprotein C-III-0; apo C-III-2; ApoC-III; sialyl apo C-III; apolipoprotein C-III-1; Apolipoprotein C III 1; ApoC III; Apolipoprotein C III 0; Apo C-III, Sialyl; Sialyl Apo C III; Sialyl Apolipoprotein C-III; Apolipoprotein C-III, Sialyl; Sialyl Apolipoprotein C III; Apo C III 2;

Is substance : O;

Details

Origin ID

D053305;

UMLS CUI

C0052191;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- APO Regimen [NCIt concept]
- APOC1 wt Allele [NCIt concept]
- APOC3 Gene [NCIt concept]
- APOC3 wt Allele [NCIt concept]
- Apolipoprotein [MedDRA Preferred Term]
- Apolipoprotein (a) (substance) [SNOMED CT concept]
- Apolipoprotein (substance) [SNOMED CT concept]
- Apolipoprotein A [LOINC component]
- Apolipoprotein A-I [MedDRA Preferred Term]
- Apolipoprotein A-I increased [MedDRA Preferred Term]
- Apolipoprotein A-II [MedDRA Preferred Term]
- Apolipoprotein B [MedDRA Preferred Term]
- Apolipoprotein B [LOINC component]
- Apolipoprotein B increased [MedDRA Preferred Term]
- Apolipoprotein C [LOINC component]
- Apolipoprotein C [MedDRA Preferred Term]
- Apolipoprotein C-I [LOINC component]
- Apolipoprotein C-I [NCIt concept]
- Apolipoprotein C-II [LOINC component]
- Apolipoprotein C-II (substance) [SNOMED CT concept]
- Apolipoprotein C-III [NCIt concept]
- Apolipoprotein C-III [LOINC component]
- Apolipoprotein C-III (substance) [SNOMED CT concept]
- Apolipoprotein C-iii [OMIM gene]
- Apolipoprotein CIII Measurement [NCIt concept]
- Apolipoprotein CIII-0 [LOINC component]
- Apolipoprotein CIII-1 [LOINC component]
- Apolipoprotein E [LOINC component]
- Cisplatin/Doxorubicin/Vincristine [NCIt concept]
- Doxorubicin/Prednisone/Vincristine Regimen [NCIt concept]
- apolipoprotein C3 [ORDO Gene]
- apolipoprotein a [SNOMED Notion]
- apolipoprotein a-i [SNOMED Notion]
- apolipoprotein a-ii [SNOMED Notion]
- apolipoprotein b [SNOMED Notion]
- apolipoprotein c [SNOMED Notion]
- apolipoprotein c-i [SNOMED Notion]
- apolipoprotein c-ii [SNOMED Notion]
- apolipoprotein c-iii [SNOMED Notion]
- apolipoprotein d [SNOMED Notion]
- apolipoprotein e [SNOMED Notion]
- apolipoprotein h [SNOMED Notion]
- lipid transporter activity [GO term]
- obsolete apolipoprotein [GO term]
Record concept(s)
- ApoC-III [MeSH concept]
- apo C-III-2 [MeSH concept]
- apolipoprotein C-III [MeSH concept]
- apolipoprotein C-III-0 [MeSH concept]
- apolipoprotein C-III-1 [MeSH concept]
- sialyl apo C-III [MeSH concept]
Related MeSH Supplementary Concept(s)
- APOC3 protein, human [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Apolipoprotein C-III [LOINC component]
- Apolipoprotein C-III (substance) [SNOMED CT concept]
- apolipoprotein c-iii [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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