MeSH definition : A transmembrane protein belonging to the tumor necrosis factor superfamily that was
originally discovered on cells of the lymphoid-myeloid lineage, including activated
T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis
and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS.;
A transmembrane protein belonging to the tumor necrosis factor superfamily that was
originally discovered on cells of the lymphoid-myeloid lineage, including activated
T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis
and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS.