protein kinase c-epsilon

Preferred Label : protein kinase c-epsilon;

MeSH definition : A protein kinase C subtype that was originally characterized as a CALCIUM-independent, serine-threonine kinase that is activated by PHORBOL ESTERS and DIACYLGLYCEROLS. It is targeted to specific cellular compartments in response to extracellular signals that activate G-PROTEIN-COUPLED RECEPTORS; TYROSINE KINASE RECEPTORS; and intracellular protein tyrosine kinase.;

MeSH synonym : kinase c-epsilon, protein; pkc epsilon serine threonine kinase; pkc-epsilon serine threonine kinase; pkc epsilon; Protein Kinase C epsilon;

CISMeF synonym : EC 2.7.1.37;

Registry Number MeSH : EC 2.7.11.13;

Is substance : O;

UNII : EC 2.7.11.13;

Details

Origin ID

D051744;

UMLS CUI

C0257694;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Protein Kinase C [NCIt concept]
- Protein kinase C, epsilon [OMIM gene]
- Serine/Threonine-Protein Kinase D1 [NCIt concept]
- Serine/Threonine-Protein Kinase D2 [NCIt concept]
- Serine/Threonine-Protein Kinase D3 [NCIt concept]
- protein kinase C epsilon [HGNC gene]
- protein serine/threonine kinase activity [GO term]
Indexing information
- KAI-1678 [MeSH Supplementary Concept]
- KIE1-1 peptide [MeSH Supplementary Concept]
- N-Myr-EAVSLKPT [MeSH Supplementary Concept]
Record concept(s)
- protein kinase C-epsilon [MeSH concept]
Related MeSH Supplementary Concept(s)
- PRKCE protein, human [MeSH Supplementary Concept]
- prkce protein, mouse [MeSH Supplementary Concept]
- prkce protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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