nf-e2-related factor 2

Preferred Label : nf-e2-related factor 2;

MeSH definition : A basic-leucine zipper transcription factor that was originally described as a transcriptional regulator controlling expression of the BETA-GLOBIN gene. It may regulate the expression of a wide variety of genes that play a role in protecting cells from oxidative damage.;

MeSH synonym : nuclear factor (erythroid-derived 2)-like 2 protein; nfe2l2 protein; NF E2 related factor 2; nuclear factor E2-Related factor 2; nuclear factor E2 related factor 2;

CISMeF synonym : nrf2 protein;

Is substance : O;

Details

Origin ID

D051267;

UMLS CUI

C0289507;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- NFE2 like bZIP transcription factor 2 [HGNC gene]
- Nuclear factor erythroid 2-like 2 [OMIM gene]
Indexing information
- 2',3'-dihydroxy-4',6'-dimethoxychalcone [MeSH Supplementary Concept]
Record concept(s)
- NF-E2-Related factor 2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- NFE2L2 protein, human [MeSH Supplementary Concept]
- Nfe2l2 protein, mouse [MeSH Supplementary Concept]
- Nfe2l2 protein, rat [MeSH Supplementary Concept]
- nfe2l2a protein, zebrafish [MeSH Supplementary Concept]
See also
- antioxidant response elements [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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