sarcosine dehydrogenase

Preferred Label : sarcosine dehydrogenase;

MeSH definition : A LIVER mitochondrial matrix flavoenzyme that catalyzes the oxidation of SARCOSINE to GLYCINE and FORMALDEHYDE. Mutation in the enzyme causes sarcosinemia, a rare autosomal metabolic defect characterized by elevated levels of SARCOSINE in BLOOD and URINE.;

MeSH synonym : n-demethylase, sarcosine; sarcosine n demethylase; dehydrogenase, sarcosine; sarcosine n-demethylase; monomethylglycine dehydrogenase; dehydrogenase, monomethylglycine;

MeSH Related Number : 37228-65-2 (CRN);

Registry Number MeSH : EC 1.5.99.1; EC 1.5.8.3;

Wikipedia link : https://en.wikipedia.org/wiki/Sarcosine dehydrogenase;

Is substance : O;

UNII : EC 1.5.8.3;

Details

Origin ID

D050892;

UMLS CUI

C0074059;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- sarcosine dehydrogenase [MeSH concept]
Related MeSH Supplementary Concept(s)
- SARDH protein, human [MeSH Supplementary Concept]
- sarcosinemia [MeSH Supplementary Concept]
- sardh protein, mouse [MeSH Supplementary Concept]
- sardh protein, rat [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Sarcosinaemia [ICD-11 Sub-sub category]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Sarcosine dehydrogenase (substance) [SNOMED CT concept]
- sarcosine dehydrogenase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

recommendations
documents concerning education
documents for patients