interferon-stimulated gene factor 3

Preferred Label : interferon-stimulated gene factor 3;

MeSH definition : A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL NUCLEUS in response to INTERFERON signaling. It consists of ISGF3-GAMMA and ISGF3-ALPHA, and it regulates expression of many interferon-responsive GENES.;

MeSH synonym : isgf3 factor; isgf3, transcription factor; transcription factor, isgf3; transcription factor isgf3; isgf3 transcription factor; ifn-stimulated gene factor 3 complex; ifn stimulated gene factor 3 complex; interferon stimulated gene factor 3;

Is substance : O;

Details

Origin ID

D050832;

UMLS CUI

C0083029;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
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- genetics [MeSH Qualifier]
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- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
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- standards [MeSH Qualifier]
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- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- ISGF3 complex [GO term]
- Interferon regulatory factor 9 [OMIM gene]
Record concept(s)
- Interferon-Stimulated gene factor 3 [MeSH concept]
Related MeSH Supplementary Concept(s)
- gamma interferon activation factor [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

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