MeSH definition : A family of transcription factors characterized by the presence of a bipartite DNA-binding
domain known as the POU domain. The POU domain contains two subdomains, a POU-specific
domain and a POU-homeodomain. The POU domain was originally identified as a region
of approximately 150 amino acids shared between the Pit-1, Oct-1, Oct-2, and Unc-86
transcription factors.;
MeSH synonym : pou proteins; pou, transcription factor; pit-oct-unc proteins; pit oct unc proteins; transcription factor pou;
A family of transcription factors characterized by the presence of a bipartite DNA-binding
domain known as the POU domain. The POU domain contains two subdomains, a POU-specific
domain and a POU-homeodomain. The POU domain was originally identified as a region
of approximately 150 amino acids shared between the Pit-1, Oct-1, Oct-2, and Unc-86
transcription factors.