nfatc transcription factors

Preferred Label : nfatc transcription factors;

MeSH definition : A family of transcription factors characterized by the presence of highly conserved calcineurin- and DNA-binding domains. NFAT proteins are activated in the CYTOPLASM by the calcium-dependent phosphatase CALCINEURIN. They transduce calcium signals to the nucleus where they can interact with TRANSCRIPTION FACTOR AP-1 or NF-KAPPA B and initiate GENETIC TRANSCRIPTION of GENES involved in CELL DIFFERENTIATION and development. NFAT proteins stimulate T-CELL activation through the induction of IMMEDIATE-EARLY GENES such as INTERLEUKIN-2.;

MeSH synonym : nf at proteins; nf-at proteins; nfat proteins; nf-at, transcription factor; nfatc proteins; nuclear factor of activated t cells, cytoplasmic; nuclear factor of activated t-cells, cytoplasmic; nuclear factors of activated t cells; nuclear factors of activated t-cells; transcription factor nf at; transcription factor nf-at; transcription factors, nfatc;

MeSH hyponym : NFAT transcription factor 2; NFAT transcription factor 1; NFAT transcription factor 3; NFAT transcription factor 4; NFATC3 Transcription Factor; Factor, NFATC3 Transcription; Transcription Factor, NFATC3; NFATx Protein; Nuclear Factor of Activated T-Cells, Cytoplasmic 3 Protein; Nuclear Factor of Activated T Cells, Cytoplasmic 3 Protein; NF-AT4 Protein; NF AT4 Protein; NFAT4 Protein; NFATC3 Protein; NFAT-2 Protein; NFAT 2 Protein; Nuclear Factor of Activated T-Cells, Cytoplasmic 1 Protein; Nuclear Factor of Activated T Cells, Cytoplasmic 1 Protein; NFATC1 Protein; NFATC1 Transcription Factor; Factor, NFATC1 Transcription; Transcription Factor, NFATC1; NF-ATc1 Protein; NF ATc1 Protein; NFAT2 Protein; NFATC4 Transcription Factor; Transcription Factor, NFATC4; NFAT3 Protein; NFATC4 Protein; Nuclear Factor of Activated T-Cells, Cytoplasmic 4 Protein; Nuclear Factor of Activated T Cells, Cytoplasmic 4 Protein; NF-AT3 Protein; NF AT3 Protein; NFATC2 Transcription Factor; Factor, NFATC2 Transcription; Transcription Factor, NFATC2; NFAT1 Protein; NFATC2 Protein; Nuclear Factor of Activated T-Cells, Cytoplasmic 2 Protein; Nuclear Factor of Activated T Cells, Cytoplasmic 2 Protein; NFAT-1 Protein; NFAT 1 Protein;

Related MeSH term : NFAT transcription factor 5; Nuclear Factor of Activated T-Cells 5 Protein; Nuclear Factor of Activated T Cells 5 Protein; OREBP Protein; Osmotic Response Element Binding Protein; NFATL1 Protein; Tonicity-Responsive Enhancer-Binding Protein; Tonicity Responsive Enhancer Binding Protein; NFAT5 Protein; NFATz Protein; TonEBP Protein;

Is substance : O;

Details

Origin ID

D050778;

UMLS CUI

C0213011;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- N-(4-chloro-2-fluorophenyl)-2-hydroxybenzamide [MeSH Supplementary Concept]
- NFAT5 protein, human [MeSH Supplementary Concept]
- Nfat5 protein, mouse [MeSH Supplementary Concept]
- Nfat5 protein, rat [MeSH Supplementary Concept]
Record concept(s)
- NFAT transcription factor 1 [MeSH concept]
- NFAT transcription factor 2 [MeSH concept]
- NFAT transcription factor 3 [MeSH concept]
- NFAT transcription factor 4 [MeSH concept]
- NFAT transcription factor 5 [MeSH concept]
- NFATC transcription factors [MeSH concept]
Related MeSH Supplementary Concept(s)
- NFATC1 protein, human [MeSH Supplementary Concept]
- NFATC2 protein, human [MeSH Supplementary Concept]
- NFATC3 protein, Xenopus [MeSH Supplementary Concept]
- NFATC3 protein, human [MeSH Supplementary Concept]
- NFATC4 protein, human [MeSH Supplementary Concept]
- Nfatc1 protein, mouse [MeSH Supplementary Concept]
- Nfatc2 protein, mouse [MeSH Supplementary Concept]
- Nfatc3 protein, mouse [MeSH Supplementary Concept]
- Nfatc4 protein, mouse [MeSH Supplementary Concept]
- Nfatc4 protein, rat [MeSH Supplementary Concept]
- transcription factor NF-AT c3 [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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