stathmin - CISMeF

Preferred Label : stathmin;

MeSH definition : A ubiquitous phosphoprotein that serves as an intracellular substrate for a variety of SIGNAL TRANSDUCTION PATHWAYS. PHOSPHORYLATION of stathmin occurs during CELL CYCLE progression, and stathmin functions as a microtubule-destabilizing protein that promotes MICROTUBULE depolymerization during INTERPHASE and late MITOSIS. Stathmin is expressed at very high levels in a variety of human CANCERS.;

MeSH synonym : leukemia-associated phosphoprotein p18; oncoprotein 18; op18 phosphoprotein; p18, leukemia-associated phosphoprotein; p18, phosphoprotein; p19, phosphoprotein; leukemia associated phosphoprotein p18; metablastin; prosolin; phosphoprotein, op18; phosphoprotein p18; phosphoprotein p19; lap18 protein;

MeSH hyponym : Alpha-Stathmin; Beta-Stathmin; Beta Stathmin; Op18b Protein; Alpha Stathmin; Op18a Protein;

Wikipedia link : https://en.wikipedia.org/wiki/Stathmin;

Is substance : O;

Details

Origin ID

D050777;

UMLS CUI

C0075189;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Stathmin 1 [OMIM gene]
- stathmin 1 [HGNC gene]
Indexing information
- Stmn3 protein, mouse [MeSH Supplementary Concept]
- Stmn3 protein, rat [MeSH Supplementary Concept]
- Stmn4 protein, mouse [MeSH Supplementary Concept]
- Stmn4 protein, rat [MeSH Supplementary Concept]
Record concept(s)
- Alpha-Stathmin [MeSH concept]
- Beta-Stathmin [MeSH concept]
- stathmin [MeSH concept]
Related MeSH Supplementary Concept(s)
- SCG10 protein, zebrafish [MeSH Supplementary Concept]
- STMN1 protein, Xenopus [MeSH Supplementary Concept]
- STMN1 protein, human [MeSH Supplementary Concept]
- STMN2 protein, human [MeSH Supplementary Concept]
- STMN3 protein, human [MeSH Supplementary Concept]
- STMN4 protein, human [MeSH Supplementary Concept]
- Stmn1 protein, mouse [MeSH Supplementary Concept]
- Stmn1 protein, rat [MeSH Supplementary Concept]
- Stmn2 protein, mouse [MeSH Supplementary Concept]
- Stmn3 protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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