MeSH definition : ONCOGENE PROTEINS from papillomavirus that deregulate the CELL CYCLE of infected cells
and lead to NEOPLASTIC CELL TRANSFORMATION. Papillomavirus E7 proteins have been shown
to interact with various regulators of the cell cycle including RETINOBLASTOMA PROTEIN
and certain cyclin-dependent kinase inhibitors.;
ONCOGENE PROTEINS from papillomavirus that deregulate the CELL CYCLE of infected cells
and lead to NEOPLASTIC CELL TRANSFORMATION. Papillomavirus E7 proteins have been shown
to interact with various regulators of the cell cycle including RETINOBLASTOMA PROTEIN
and certain cyclin-dependent kinase inhibitors.