succinate-semialdehyde dehydrogenase

Preferred Label : succinate-semialdehyde dehydrogenase;

MeSH definition : An enzyme that plays a role in the GLUTAMATE and butanoate metabolism pathways by catalyzing the oxidation of succinate semialdehyde to SUCCINATE using NAD as a coenzyme. Deficiency of this enzyme, causes 4-hydroxybutyricaciduria, a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA).;

MeSH synonym : nad( )-dependent succinic semialdehyde dehydrogenase; dehydrogenase, succinate-semialdehyde; dehydrogenase, succinate semialdehyde; semialdehyde dehydrogenase, succinate; succinic semialdehyde dehydrogenase; dehydrogenase, succinic semialdehyde; semialdehyde dehydrogenase, succinic; succinate semialdehyde dehydrogenase;

MeSH Related Number : 9028-95-9 (CRN);

Registry Number MeSH : EC 1.2.1.24;

Wikipedia link : https://en.wikipedia.org/wiki/Succinate-semialdehyde dehydrogenase;

Is substance : O;

UNII : EC 1.2.1.24;

Details

Origin ID

D050644;

UMLS CUI

C0075426;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Succinate semialdehyde dehydrogenase [LOINC component]
- Succinate-semialdehyde dehydrogenase (substance) [SNOMED CT concept]
- succinate-semialdehyde dehydrogenase [SNOMED Notion]
Record concept(s)
- Succinate-Semialdehyde dehydrogenase [MeSH concept]
Related MeSH Supplementary Concept(s)
- ALDH5A1 protein, human [MeSH Supplementary Concept]
- Aldh5a1 protein, mouse [MeSH Supplementary Concept]
- Aldh5a1 protein, rat [MeSH Supplementary Concept]
- gabD protein, E coli [MeSH Supplementary Concept]
- succinic semialdehyde dehydrogenase deficiency [MeSH Supplementary Concept]
See also inter- (CISMeF)
- 4-hydroxybutyric aciduria [ICD-11 More detail]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Succinate semialdehyde dehydrogenase [LOINC component]
- Succinate-semialdehyde dehydrogenase (substance) [SNOMED CT concept]
- Succinic semialdehyde dehydrogenase [OBSOLETE LOINC component]
- succinate-semialdehyde dehydrogenase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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