metabolic detoxication, phase ii

Preferred Label : metabolic detoxication, phase ii;

MeSH definition : The conjugation of exogenous substances with various hydrophilic substituents to form water soluble products that are excretable in URINE. Phase II modifications include GLUTATHIONE conjugation; ACYLATION; and AMINATION. Phase II enzymes include GLUTATHIONE TRANSFERASE and GLUCURONOSYLTRANSFERASE. In a sense these reactions detoxify phase I reaction products.;

MeSH synonym : conjugative metabolic detoxication; conjugative metabolic detoxications; detoxication, conjugative metabolic; detoxications, conjugative metabolic; detoxifications, phase ii; metabolic detoxication, conjugative; phase ii detoxification; metabolic detoxications, conjugative; detoxification, phase ii; phase ii detoxifications; metabolic detoxification, phase ii;

Details

Origin ID

D050217;

UMLS CUI

C1563755;

Allowable qualifiers
- ethnology [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Currated CISMeF NLP mapping
- Phase II Detoxification [NCIt concept]
Record concept(s)
- metabolic detoxication, phase II [MeSH concept]
See also
- antioxidant response elements [MeSH Descriptor]
- protein processing, post-translational [MeSH Descriptor]
Semantic type(s)
- Organism Function [UMLS semantic type]
UMLS correspondences (same concept)
- Phase II Detoxification [NCIt concept]

Keyword's position in hierarchy(ies) :

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