MAP kinase kinase 1

Preferred Label : MAP kinase kinase 1;

MeSH definition : An abundant 43-kDa mitogen-activated protein kinase kinase subtype with specificity for MITOGEN-ACTIVATED PROTEIN KINASE 1 and MITOGEN-ACTIVATED PROTEIN KINASE 3.;

MeSH synonym : mek-1 protein kinase; mek1 protein kinase; mitogen activated protein kinase kinase 1; mkk 1 protein kinase; mapk kinase 1; mek 1 protein kinase; mitogen-activated protein kinase kinase 1; mkk-1 protein kinase; mkk1 protein kinase; map2k1 protein;

CISMeF synonym : EC 2.7.1.-;

Registry Number MeSH : EC 2.7.12.2;

Is substance : O;

UNII : EC 2.7.12.2;

Details

Origin ID

D048369;

UMLS CUI

C0173879;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Dual Specificity Mitogen-Activated Protein Kinase Kinase 1 [NCIt concept]
Indexing information
- 4-(2-fluoro-4-iodophenylamino)-1H-indazole-5-carboxylic acid (2-hydroxyethoxy)amide [MeSH Supplementary Concept]
- SMK-17 [MeSH Supplementary Concept]
- binimetinib [MeSH Supplementary Concept]
- cobimetinib [MeSH Supplementary Concept]
- trametinib [MeSH Supplementary Concept]
Record concept(s)
- MAP kinase kinase 1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- MAP2K1 protein, human [MeSH Supplementary Concept]
- MAP2K1 protein, zebrafish [MeSH Supplementary Concept]
- MEK1 protein, arabidopsis [MeSH Supplementary Concept]
- Map2k1 protein, mouse [MeSH Supplementary Concept]
- Mek1 protein, S pombe [MeSH Supplementary Concept]
- Mek1 protein, nicotiana tabacum [MeSH Supplementary Concept]
- mek-1 protein, C elegans [MeSH Supplementary Concept]
- pek-1 protein, C elegans [MeSH Supplementary Concept]
See also (suggested by CISMeF)
- pimasertib [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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