JNK Mitogen-Activated protein kinases

Preferred Label : JNK Mitogen-Activated protein kinases;

MeSH definition : A subgroup of mitogen-activated protein kinases that activate TRANSCRIPTION FACTOR AP-1 via the phosphorylation of C-JUN PROTEINS. They are components of intracellular signaling pathways that regulate CELL PROLIFERATION; APOPTOSIS; and CELL DIFFERENTIATION.;

MeSH synonym : amino-terminal kinase, c-jun; c-jun n-terminal kinase; jun-nh2-terminal kinase; jun-nh2-terminal kinases; n-terminal kinase, c-jun; c jun n terminal kinase; jun nh2 terminal kinases; jun nh2 terminal kinase; c-jun amino-terminal kinase; c jun amino terminal kinase; JNK mitogen activated protein kinases; jun N-Terminal Kinase; Kinase, jun N-Terminal; N-Terminal Kinase, jun; jun N Terminal Kinase;

CISMeF synonym : EC 2.7.1.37;

Registry Number MeSH : EC 2.7.11.24;

MeSH annotation : note specifics;

Is substance : O;

UNII : EC 2.7.11.24;

Details

Origin ID

D048031;

UMLS CUI

C0248813;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Mitogen-Activated Protein Kinase 8 [NCIt concept]
- Serine/Threonine-Protein Kinase NLK [NCIt concept]
- mitogen-activated protein kinase 8 [HGNC gene]
Indexing information
- 4-(2,3-dihydro-1,4-benzodioxin-6-yl)-2,4-dihydro-5-((5-nitro-2-thiazolyl)thio)-3H-1,2,4-triazol-3-one [MeSH Supplementary Concept]
- 4-(9-(tetrahydrofuran-3-yl))-8-(2,4,6-trifluorophenylamino)-9H-purin-2-ylaminocyclohexan-1-ol [MeSH Supplementary Concept]
- 5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine [MeSH Supplementary Concept]
- CC 401 [MeSH Supplementary Concept]
- Tat-JBD peptide [MeSH Supplementary Concept]
Record concept(s)
- JNK Mitogen-Activated protein kinases [MeSH concept]
Related MeSH Supplementary Concept(s)
- KGB-1 protein, C elegans [MeSH Supplementary Concept]
- bsk protein, Drosophila [MeSH Supplementary Concept]
- c-jun N-terminal kinase Bim(EL), rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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