receptors, tumor necrosis factor, type i

Preferred Label : receptors, tumor necrosis factor, type i;

MeSH definition : A tumor necrosis factor receptor subtype that has specificity for TUMOR NECROSIS FACTOR ALPHA and LYMPHOTOXIN ALPHA. It is constitutively expressed in most tissues and is a key mediator of tumor necrosis factor signaling in the vast majority of cells. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.;

MeSH synonym : tumor necrosis factor receptor 1a; 120a antigen, cd; antigen, cd120a; cd 120a antigen; tnfr p60; tnfrsf1a (tumor necrosis factor receptor superfamily, member 1a); tumor necrosis factor receptor superfamily, member 1a; tumor necrosis factor receptor type 1; antigens, cd120a; antigen, cd 120a; cd120a antigen; cd120a antigens; receptors, tumor necrosis factor, member 1a; tnfr-i; tnfr1; tnfrsf1a receptor; receptor, tnfrsf1a; tumor necrosis factor receptor type i;

Is substance : O;

Details

Origin ID

D047888;

UMLS CUI

C0255808;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Tumor necrosis factor receptor superfamily member 1A [LOINC component]
Indexing information
- PLAD.Fc fusion protein [MeSH Supplementary Concept]
Record concept(s)
- receptors, tumor necrosis factor, type I [MeSH concept]
Related MeSH Supplementary Concept(s)
- PEGylated soluble tumor necrosis factor receptor I [MeSH Supplementary Concept]
- PEGylated tumor necrosis factor alpha receptor 1 [MeSH Supplementary Concept]
- TNFRSF1A protein, human [MeSH Supplementary Concept]
- Tnfrsf1a protein, mouse [MeSH Supplementary Concept]
- Tnfrsf1a protein, rat [MeSH Supplementary Concept]
- recombinant human tumor necrosis factor-binding protein-1 [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- CD120a [LOINC component]
- Lymphocyte antigen CD120A (substance) [SNOMED CT concept]
- Tumor necrosis factor receptor superfamily member 1A [LOINC component]
- lymphocyte antigen cd120a [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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