recombinant human tumor necrosis factor-binding protein-1

Preferred Label : recombinant human tumor necrosis factor-binding protein-1;

MeSH note : a recombinant human soluble p55 tumor necrosis factor binding protein for the treatment of a number of disorders, including Crohn's disease, psoriasis and psoriatic arthritis; TNFbp (pharmacologic) is the dimeric polyethylene glycol linked form of the type I soluble receptor of tumor necrosis factor (TNF) that acts as a TNF inhibitor;

CISMeF synonym : PEG-linked dimeric type I soluble receptor of TNF; onercept; tumor necrosis factor receptor type I, P55 soluble fragment;

MeSH synonym : r-hTBP-1; recombinant human soluble p55 tumour necrosis factor receptor; TNFRp55; glycoprotein TNF-BP (tumor necrosis factor-binding protein) (human disulfide variant 1);

MeSH Hyperonym : TNF-sR55; Tumor Necrosis Factor Receptor 55; TNF Receptor p55; Receptor(55), TNF;

Related MeSH term : PEG-(rsTNF-RI)2; PEG-linked dimeric form of rsTNF-RI;

MeSH Related Number : 199685-57-9;

Is substance : O;

UNII : 1IEO802L3J;

Details

Origin ID

C069521;

UMLS CUI

C1100612;

Automatic exact mappings (from CISMeF team)
- Onercept [NCIt concept]
MeSH indexing information
- polyethylene glycols [MeSH Descriptor]
- recombinant proteins [MeSH Descriptor]
MeSH term(s) associated for indexing
- receptors, tumor necrosis factor, type i [MeSH Descriptor]
- tumor necrosis factor decoy receptors [MeSH Descriptor]
Record concept(s)
- PEG-linked dimeric type I soluble receptor of TNF [MeSH concept]
- onercept [MeSH concept]
- recombinant human tumor necrosis factor-binding protein-1 [MeSH concept]
- tumor necrosis factor receptor type I, P55 soluble fragment [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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