PPAR alpha - CISMeF

Preferred Label : PPAR alpha;

MeSH definition : A nuclear transcription factor. Heterodimerization with RETINOID X RECEPTOR GAMMA is important to metabolism of LIPIDS. It is the target of FIBRATES to control HYPERLIPIDEMIAS.;

MeSH synonym : pparalpha; peroxisome proliferator-activated receptor alpha; peroxisome proliferator activated receptor alpha;

Wikipedia link : https://en.wikipedia.org/wiki/Peroxisome proliferator-activated receptor alpha;

Is substance : O;

Details

Origin ID

D047493;

UMLS CUI

C0166415;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Peroxisome Proliferator-Activated Receptor Alpha [NCIt concept]
- Peroxisome proliferator-activated receptor-alpha [OMIM Phenotype]
Indexing information
- (S)-2-(2,4-hexadienoyl)-7-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid [MeSH Supplementary Concept]
- 1-(4-(2-(5-methyl-2-p-tolyloxazol-4-yl)ethoxy)benzyl)piperidine-2-carboxylic acid [MeSH Supplementary Concept]
- 2-((3-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic acid [MeSH Supplementary Concept]
- 2-((4-(((2-methoxyethyl)(6-(3-(trifluoromethyl)phenyl)pyrimidin-4-yl)amino)methyl)phenyl)sulfanyl)-2-methylpropanoic acid [MeSH Supplementary Concept]
- 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid [MeSH Supplementary Concept]
- 2-(4-(2-Fluoro-benzenesulphonyl)-piperazin-1-yl)-3-(4-(2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy)phenyl)propionic acid [MeSH Supplementary Concept]
- 2-(4-chlorophenoxy)-3-phenylpropanoic acid [MeSH Supplementary Concept]
- 2-(4-methoxy-3-((pyrene-1-carboxamido)methyl)benzyl)butanoic acid [MeSH Supplementary Concept]
- 2-ethyl-5-(3-(2-chloro-4-(trifluoromethoxy)phenoxy)propoxy)-2,3-dihydro-1-benzofuran-2-carboxylic acid [MeSH Supplementary Concept]
- 2-methyl-6-(3-(2-phenyloxazol-4-ylmethoxy)propoxymethyl)benzoic acid [MeSH Supplementary Concept]
- 3-(3-(1-carboxy-1-methylethoxy)phenyl)piperidine-1-carboxylic acid 4-trifluoromethylbenzyl ester [MeSH Supplementary Concept]
- 3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)-2-(2-(2-nitrophenoxy)acetylamino)propionic acid [MeSH Supplementary Concept]
- CG 301269 [MeSH Supplementary Concept]
- MK-886 [MeSH Supplementary Concept]
- N-octadecyl-N'-propylsulfamide [MeSH Supplementary Concept]
- elaidyl-sulfamide [MeSH Supplementary Concept]
- lobeglitazone [MeSH Supplementary Concept]
- methyl 7-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)coumarin-7-carboxylate [MeSH Supplementary Concept]
- muraglitazar [MeSH Supplementary Concept]
- naveglitazar [MeSH Supplementary Concept]
- ombuin-3-O-glucopyranoside [MeSH Supplementary Concept]
- peliglitazar [MeSH Supplementary Concept]
- sipoglitazar [MeSH Supplementary Concept]
Record concept(s)
- PPAR alpha [MeSH concept]
Related MeSH Supplementary Concept(s)
- PPARA protein, human [MeSH Supplementary Concept]
- Ppara protein, mouse [MeSH Supplementary Concept]
- Ppara protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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