furin - CISMeF

Preferred Label : furin;

MeSH definition : A proprotein convertase with specificity for the proproteins of PROALBUMIN; COMPLEMENT 3C; and VON WILLEBRAND FACTOR. It has specificity for cleavage near paired ARGININE residues that are separated by two amino acids.;

MeSH synonym : paired basic amino acid cleaving enzyme; processing enzyme, dibasic; dibasic processing enzyme; furin protein; spc1 proteinase;

MeSH Related Number : EC 3.4.21.75;

Registry Number MeSH : EC 3.4.21.75;

Wikipedia link : https://en.wikipedia.org/wiki/Furin;

Is substance : O;

UNII : EC 3.4.21.75;

Details

Origin ID

D045683;

UMLS CUI

C0287990;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- FURIN Gene [NCIt concept]
- Furin [NCIt concept]
Indexing information
- 5-amino-4-acetylamino-3-(4-methylphenylamino)1H-pyrazole [MeSH Supplementary Concept]
- hexaarginine amide [MeSH Supplementary Concept]
- nonaarginine [MeSH Supplementary Concept]
Record concept(s)
- furin [MeSH concept]
Related MeSH Supplementary Concept(s)
- FURIN protein, human [MeSH Supplementary Concept]
- Fur1 protein, drosophila [MeSH Supplementary Concept]
- Fur2 protein, Drosophila [MeSH Supplementary Concept]
- Furin protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Furin [NCIt concept]
- Furin (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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