proprotein convertase 1

Preferred Label : proprotein convertase 1;

MeSH definition : A CALCIUM-dependent endopeptidase that has specificity for cleavage at ARGININE that is near paired basic residues. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN; PRORENIN; proenkephalins; prodynorphin; prosomatostatin; and PROINSULIN.;

MeSH synonym : convertase spc3, proprotein; prohormone convertase, pc1; prohormone convertase 3; convertase, pc1 prohormone; prohormone convertase 1; neuroendocrine convertase pc1; convertase 1, proprotein; pc1 prohormone convertase; pc3 endoprotease; endoprotease, pc3; pc3 prohormone convertase; convertase, pc3 prohormone; prohormone convertase, pc3; convertase pc1, neuroendocrine; proprotein convertase spc3; proinsulin convertase 1; pc1 endoprotease; endoprotease, pc1;

Registry Number MeSH : EC 3.4.21.93;

Wikipedia link : https://en.wikipedia.org/wiki/Proprotein convertase 1;

Is substance : O;

UNII : EC 3.4.21.93;

Details

Origin ID

D045664;

UMLS CUI

C0135615;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- proprotein convertase 1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- PCSK1 protein, human [MeSH Supplementary Concept]
- Pcsk1 protein, mouse [MeSH Supplementary Concept]
- proprotein convertase 1 3 deficiency [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Proprotein convertase 1 (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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