MeSH definition : A family of DNA repair enzymes that recognize damaged nucleotide bases and remove
them by hydrolyzing the N-glycosidic bond that attaches them to the sugar backbone
of the DNA molecule. The process called BASE EXCISION REPAIR can be completed by a
DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE which excises the remaining RIBOSE sugar
from the DNA.;
MeSH synonym : dna n-glycosidase; glycosylases, dna; dna glycosylase; glycosylase, dna; dna n glycosidase;
MeSH hyponym : methylpurine DNA glycosylase; DNA Glycosylase, Methylpurine; Glycosylase, Methylpurine DNA;
MeSH Related Number : methylpurine DNA glycosylase;
Registry Number MeSH : EC 3.2.2.-;
Related CAS MeSH : EC 3.2.2.- (Methylpurine DNA glycosylase);
Wikipedia link : https://en.wikipedia.org/wiki/Dna glycosylases;
A family of DNA repair enzymes that recognize damaged nucleotide bases and remove
them by hydrolyzing the N-glycosidic bond that attaches them to the sugar backbone
of the DNA molecule. The process called BASE EXCISION REPAIR can be completed by a
DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE which excises the remaining RIBOSE sugar
from the DNA.
http://www.e-cancer.fr/content/download/58351/531984/file/chir_prophy_predi_gene_polypose.pdf 2009 false France French intestinal polyps genetic predisposition to disease adenomatous polyposis coli colorectal neoplasms enterostomy duodenal neoplasms adenoma duodenal neoplasms DNA glycosylases guideline