aryldialkylphosphatase

Preferred Label : aryldialkylphosphatase;

MeSH definition : An enzyme which catalyzes the hydrolysis of an aryl-dialkyl phosphate to form dialkyl phosphate and an aryl alcohol. It can hydrolyze a broad spectrum of organophosphate substrates and a number of aromatic carboxylic acid esters. It may also mediate an enzymatic protection of LOW DENSITY LIPOPROTEINS against oxidative modification and the consequent series of events leading to ATHEROMA formation. The enzyme was previously regarded to be identical with Arylesterase (EC 3.1.1.2).;

MeSH synonym : acid anhydrase, organophosphorus; acid anhydrolase, organophosphorus; acid hydrolase, organophosphorus; anhydrase, opa; anhydrase, organophosphorus acid; anhydrolase, organophosphorus acid; arylalkylphosphatase; aryl-dialkyl phosphatase; homocysteine thiolactone hydrolase; hydrolase, homocysteine thiolactone; opa anhydrase; oph enzyme; organophosphorus acid anhydrase; organophosphorus acid anhydrolase; organophosphorus hydrolase; paraoxonase; thiolactone hydrolase, homocysteine; organophosphorus acid hydrolase; hydrolase, organophosphorus acid; hydrolase, organophosphorus; aryl dialkyl phosphatase; phosphatase, aryl-dialkyl; enzyme, oph;

MeSH hyponym : Paraoxonase-2; Paraoxonase-1; Paraoxonase 1; Paraoxonase 2;

MeSH Related Number : Paraoxonase-1; Paraoxonase-2; EC 3.1.8.1;

Registry Number MeSH : EC 3.1.8.1;

Related CAS MeSH : EC 3.1.8.1 (Paraoxonase-1); EC 3.1.8.1 (Paraoxonase-2);

MeSH annotation : X refs PARAOXONASE-1 and PARAOXONASE-2 see SCR for organism specific terms; entry terms PARAOXONASE-1, and PARAOXONASE-2 see SCR for organism specific terms;

Wikipedia link : https://en.wikipedia.org/wiki/Paraoxonase-1;

Is substance : O;

UNII : EC 3.1.8.1;

Details

Origin ID

D043303;

UMLS CUI

C0163401;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Aryldialkylphosphatase (substance) [SNOMED CT concept]
- Arylesterase (substance) [SNOMED CT concept]
- Diisopropyl-fluorophosphatase (substance) [SNOMED CT concept]
- Paraoxonase 1 [OMIM Phenotype]
- Paraoxonase 2 [OMIM gene]
- Serum Paraoxonase/Arylesterase 2 [NCIt concept]
- paraoxonase 1 [HGNC gene]
- paraoxonase 1 [ORDO Gene]
- paraoxonase 2 [HGNC gene]
- paraoxonase 2 [ORDO Gene]
Currated CISMeF NLP mapping
- Aryldialkylphosphatase [NCIt concept]
Record concept(s)
- Paraoxonase-1 [MeSH concept]
- Paraoxonase-2 [MeSH concept]
- aryldialkylphosphatase [MeSH concept]
Related MeSH Supplementary Concept(s)
- MEC-6 protein, C elegans [MeSH Supplementary Concept]
- POML-1 protein, C elegans [MeSH Supplementary Concept]
- PON1 protein, human [MeSH Supplementary Concept]
- PON1 protein, mouse [MeSH Supplementary Concept]
- PON2 protein, human [MeSH Supplementary Concept]
- PON2 protein, mouse [MeSH Supplementary Concept]
- PON3 protein, human [MeSH Supplementary Concept]
- PON3 protein, mouse [MeSH Supplementary Concept]
- Pon1 protein, rat [MeSH Supplementary Concept]
- paraoxonase 2, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Aryldialkylphosphatase [NCIt concept]
- Aryldialkylphosphatase (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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