carboxylesterase

Preferred Label : carboxylesterase;

MeSH definition : Carboxylesterase is a serine-dependent esterase with wide substrate specificity. The enzyme is involved in the detoxification of XENOBIOTICS and the activation of ester and of amide PRODRUGS.;

MeSH synonym : lipase, carboxylester; ali esterase; ali-esterase; amidase, isocarboxazid; b esterase; b-esterase; cap hydrolyzing enzyme; cap-hydrolyzing enzyme; capsaicin hydrolyzing enzyme; carboxyesterase; carboxylester lipase; carboxylesterase, non-specific; carboxylic ester hydrolase; esterase, non-specific; esterase, nonspecific; esterase, procaine; naproxen esterase; non specific carboxylesterase; non specific esterase; non-specific carboxylesterase; non-specific esterase; nonspecific esterase; procaine esterase; isocarboxazid amidase; enzyme, cap-hydrolyzing; capsaicin-hydrolyzing enzyme; enzyme, capsaicin-hydrolyzing; carboxylate esterase; esterase, carboxylate; carboxylesterase b; ester hydrolase, carboxylic; hydrolase, carboxylic ester; esterase, naproxen;

MeSH hyponym : esterase ES-1A; esterase 6A; esterase 3; esterase 10; hydrolase S; esterase 8; esterase 13; ES-1A, Esterase; Esterase ES 1A;

CISMeF hyponym : EC 3.1.1.1;

MeSH Related Number : esterase 13; hydrolase S; esterase 6A; esterase 8; esterase ES-1A; esterase 10; esterase 3; 9016-18-6 (CRN); EC 3.1.1.1;

Registry Number MeSH : EC 3.1.1.1;

Related CAS MeSH : EC 3.1.1.1 (Esterase 13); EC 3.1.1.1 (Hydrolase S); EC 3.1.1.1 (Esterase 6A); EC 3.1.1.1 (Esterase 8); EC 3.1.1.1 (Esterase ES-1A); EC 3.1.1.1 (Esterase 10); EC 3.1.1.1 (Esterase 3);

Wikipedia link : https://en.wikipedia.org/wiki/Carboxylesterase;

Is substance : O;

UNII : EC 3.1.1.1;

Details

Origin ID

D043182;

UMLS CUI

C0054741;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Carboxyl-ester lipase [OMIM gene]
- Esterase [NCIt concept]
- Esterase (substance) [SNOMED CT concept]
- Esterase C [OMIM Phenotype]
- Nonspecific esterase stain (substance) [SNOMED CT concept]
- Paraoxonase 1 [OMIM Phenotype]
- carboxylesterase activity [GO term]
- carboxylic ester hydrolase activity [GO term]
Currated CISMeF NLP mapping
- Carboxylesterase [NCIt concept]
- Carboxylesterase (substance) [SNOMED CT concept]
- carboxylesterase [SNOMED Notion]
False automatic mappings
- Esterase b [OMIM Phenotype]
Record concept(s)
- carboxylesterase [MeSH concept]
- esterase 10 [MeSH concept]
- esterase 13 [MeSH concept]
- esterase 3 [MeSH concept]
- esterase 6A [MeSH concept]
- esterase 8 [MeSH concept]
- esterase ES-1A [MeSH concept]
- hydrolase S [MeSH concept]
Related MeSH Supplementary Concept(s)
- CES2 protein, human [MeSH Supplementary Concept]
- Ces1c protein, mouse [MeSH Supplementary Concept]
- Ces1d protein, mouse [MeSH Supplementary Concept]
- Ces1d protein, rat [MeSH Supplementary Concept]
- Ces2c protein, mouse [MeSH Supplementary Concept]
- ESA4 protein, human [MeSH Supplementary Concept]
- ESD protein, human [MeSH Supplementary Concept]
- EST5B protein, drosophila [MeSH Supplementary Concept]
- Es12 protein, mouse [MeSH Supplementary Concept]
- Es29 protein, mouse [MeSH Supplementary Concept]
- Es30 protein, mouse [MeSH Supplementary Concept]
- Est-6 protein, Drosophila [MeSH Supplementary Concept]
- FE4 protein, myzus persicae [MeSH Supplementary Concept]
- LipB protein, bacillus subtilis [MeSH Supplementary Concept]
- carboxylesterase 1A1, human [MeSH Supplementary Concept]
- carboxylesterase 1A2, human [MeSH Supplementary Concept]
- carboxylesterase Est30, bacillus [MeSH Supplementary Concept]
- cauxin protein, felis catus [MeSH Supplementary Concept]
- cel.1 protein, zebrafish [MeSH Supplementary Concept]
- esterase 1F, mouse [MeSH Supplementary Concept]
- esterase-S, drosophila [MeSH Supplementary Concept]
- hydrolase A protein, rat [MeSH Supplementary Concept]
- hydrolase B, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Carboxylesterase [NCIt concept]
- Carboxylesterase (substance) [SNOMED CT concept]
- Esterase b [OMIM Phenotype]
- carboxylesterase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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