electron transport complex I

Preferred Label : electron transport complex I;

MeSH definition : A flavoprotein and iron sulfur-containing oxidoreductase complex that catalyzes the conversion of UBIQUINONE to ubiquinol. In MITOCHONDRIA the complex also couples its reaction to the transport of PROTONS across the internal mitochondrial membrane. The NADH DEHYDROGENASE component of the complex can be isolated and is listed as EC 1.6.99.3.;

MeSH synonym : respiratory complex i;

CISMeF synonym : mitochondrial electron transport complex I; bacterial electron transport complex I;

MeSH hyponym : NADH dehydrogenase (Ubiquinone); NADH Dehydrogenase Complex 1; NADH Dehydrogenase I; NADH DH I; Ubiquinone Reductase; NADH-Coenzyme Q Reductase; NADH Coenzyme Q Reductase; NADH-CoQ Reductase; NADH CoQ Reductase; NADH-Ubiquinone Oxidoreductase; NADH Ubiquinone Oxidoreductase; Oxidoreductase, NADH-Ubiquinone; NADH-Ubiquinone Reductase; NADH Ubiquinone Reductase; Reductase, NADH-Ubiquinone; Rotenone-Sensitive Mitochondrial NADH-Ubiquinone Oxidoreductase; Rotenone Sensitive Mitochondrial NADH Ubiquinone Oxidoreductase; Complex I Dehydrogenase; Dehydrogenase, Complex I; NADH Q1 Oxidoreductase; Oxidoreductase, NADH Q1;

MeSH Related Number : NADH dehydrogenase (Ubiquinone); EC 1.6.5.3;

Registry Number MeSH : EC 1.6.5.3;

Related CAS MeSH : EC 1.6.5.3 (NADH dehydrogenase (Ubiquinone));

Wikipedia link : https://en.wikipedia.org/wiki/Electron transport complex i;

Is substance : O;

UNII : EC 7.1.1.2;

Details

Origin ID

D042967;

UMLS CUI

C2363240;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- NADH Dehydrogenase (Ubiquinone) [NCIt concept]
- NADH cytochrome C reductase [LOINC component]
- NADH dehydrogenase [LOINC component]
- NADH:ubiquinone oxidoreductase subunit A5 [HGNC gene]
- Reduced nicotinamide adenine dinucleotide dehydrogenase (ubiquinon) (substance) [SNOMED CT concept]
- nadh dehydrogenase (ubiquinon) [SNOMED Notion]
- respiratory chain complex I [GO term]
Indexing information
- 2-(4-(4-fluorobutyl)benzylsulfanyl)-3-methylchromen-4-one [MeSH Supplementary Concept]
- 7-chloro-3-methyl-2-(4-(4-(trifluoromethoxy)benzyl)phenyl)quinolin-4(1H)-one [MeSH Supplementary Concept]
- BAY-84-7296 [MeSH Supplementary Concept]
- NuoH protein, E coli [MeSH Supplementary Concept]
- SL-2-25 [MeSH Supplementary Concept]
- ajudazol A [MeSH Supplementary Concept]
- ajudazol B [MeSH Supplementary Concept]
- circumdatin H [MeSH Supplementary Concept]
- eliamid [MeSH Supplementary Concept]
- fenpyroximate [MeSH Supplementary Concept]
Record concept(s)
- NADH dehydrogenase (Ubiquinone) [MeSH concept]
- electron transport complex I [MeSH concept]
Related MeSH Supplementary Concept(s)
- MT-ND3 protein, human [MeSH Supplementary Concept]
- MT-ND5 protein, human [MeSH Supplementary Concept]
- NAD2 protein, Arabidopsis [MeSH Supplementary Concept]
- NAD4 protein, arabidopsis [MeSH Supplementary Concept]
- ND-13A protein, Drosophila [MeSH Supplementary Concept]
- ND-42 protein, Drosophila [MeSH Supplementary Concept]
- NDUFA1 protein, human [MeSH Supplementary Concept]
- NDUFA11 protein, human [MeSH Supplementary Concept]
- NDUFA4L2 protein, human [MeSH Supplementary Concept]
- NDUFA4L2 protein, mouse [MeSH Supplementary Concept]
- NDUFA9 protein, human [MeSH Supplementary Concept]
- NDUFAB1 protein, human [MeSH Supplementary Concept]
- NDUFB11 protein, human [MeSH Supplementary Concept]
- NDUFB6 protein, human [MeSH Supplementary Concept]
- NDUFB8 protein, human [MeSH Supplementary Concept]
- NDUFB8 protein, mouse [MeSH Supplementary Concept]
- NDUFC2 protein, human [MeSH Supplementary Concept]
- NDUFC2 protein, mouse [MeSH Supplementary Concept]
- NDUFS4 protein, arabidopsis [MeSH Supplementary Concept]
- NDUFS4 protein, human [MeSH Supplementary Concept]
- NDUFS5 protein, human [MeSH Supplementary Concept]
- NDUFS8 protein, Arabidopsis [MeSH Supplementary Concept]
- NDUFV1 protein, human [MeSH Supplementary Concept]
- NDUFV1 protein, mouse [MeSH Supplementary Concept]
- NDUFV3 protein, human [MeSH Supplementary Concept]
- NDUFV3 protein, rat [MeSH Supplementary Concept]
- NUO-1 protein, C elegans [MeSH Supplementary Concept]
- Ndi1 protein, S cerevisiae [MeSH Supplementary Concept]
- Ndufa1 protein, mouse [MeSH Supplementary Concept]
- Ndufa13 protein, rat [MeSH Supplementary Concept]
- Ndufa4l2 protein, rat [MeSH Supplementary Concept]
- Ndufa7 protein, mouse [MeSH Supplementary Concept]
- Ndufa9 protein, mouse [MeSH Supplementary Concept]
- Ndufb11 protein, mouse [MeSH Supplementary Concept]
- Ndufb6 protein, mouse [MeSH Supplementary Concept]
- Ndufc2 protein, rat [MeSH Supplementary Concept]
- Ndufs4 protein, mouse [MeSH Supplementary Concept]
- NuoB protein, E coli [MeSH Supplementary Concept]
- NuoCD protein, E coli [MeSH Supplementary Concept]
- NuoE protein, E coli [MeSH Supplementary Concept]
- NuoG protein, E coli [MeSH Supplementary Concept]
- NuoN protein, E coli [MeSH Supplementary Concept]
- gammaCAL1 protein, arabidopsis [MeSH Supplementary Concept]
- gammaCAL2 protein, arabidopsis [MeSH Supplementary Concept]
- mitochondrial complex I deficiency [MeSH Supplementary Concept]
- ndufa7 protein, zebrafish [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

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