eukaryotic initiation Factor-5

Preferred Label : eukaryotic initiation Factor-5;

MeSH definition : A eukaryotic initiation factor that interacts with the 40S initiation complex and promotes the hydrolysis of the bound GTP. The hydrolysis of GTP causes the release of EUKARYOTIC INITIATION FACTOR-2 and EUKARYOTIC INITIATION FACTOR-3 from the 40S subunit and the subsequent joining of the 60S ribosomal subunit to the 40S complex to form the functional 80S initiation complex;

MeSH synonym : peptide initiation factor eif 5; initiation factor-5, eukaryotic; eukaryotic peptide initiation factor-5; eukaryotic peptide initiation factor 5; peptide initiation factor eif-5; eif-5; eukaryotic initiation factor 5;

Is substance : O;

Details

Origin ID

D040061;

UMLS CUI

C0058991;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- EIF5 Gene [NCIt concept]
- EIF5 wt Allele [NCIt concept]
- Eukaryotic Translation Initiation Factor 5 [NCIt concept]
- Eukaryotic translation initiation factor 5 [OMIM gene]
Pharmacological action(s)
- GTP phosphohydrolase activators [MeSH Descriptor]
Record concept(s)
- eukaryotic initiation Factor-5 [MeSH concept]
Related MeSH Supplementary Concept(s)
- EIF5Al1 protein, human [MeSH Supplementary Concept]
- eIF5A protein, S cerevisiae [MeSH Supplementary Concept]
- krasavietz protein, drosophila [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients