semaphorins - CISMeF

Preferred Label : semaphorins;

MeSH definition : A family of proteins that mediate axonal guidance. Semaphorins act as repulsive cues for neuronal GROWTH CONES and bind to receptors on their filopodia. At least 20 different molecules have been described and divided into eight classes based on domain organization and species of origin. Classes 1 and 2 are invertebrate, classes 3-7 are vertebrate, and class V are viral. Semaphorins may be secreted (classes 2, 3, and V), transmembrane (classes 1, 4, 5, and 6), or membrane-anchored (class 7). All semaphorins possess a common 500-amino acid extracellular domain which is critical for receptor binding and specificity, and is also found in plexins and scatter factor receptors. Their C termini are class-specific and may contain additional sequence motifs.;

MeSH synonym : semaphorin;

CISMeF synonym : V semaphorins, class;

MeSH hyponym : class 5 semaphorins; class 6 semaphorins; class 4 semaphorins; class 1 semaphorins; class 3 semaphorins; class 7 semaphorins; class V semaphorins; class 2 semaphorins; Semaphorins, Class 2; Semaphorin-2; Semaphorin 2; Semaphorins, Class 3; Semaphorin-3; Semaphorin 3; Semaphorins, Class V; Semaphorin-V; Semaphorin V; Semaphorins, Class 5; Semaphorin-5; Semaphorin 5; Semaphorins, Class 6; Semaphorin-6; Semaphorin 6; Semaphorins, Class 7; Semaphorin-7; Semaphorin 7; Semaphorins, Class 1; Sema 1; Semaphorin-1; Semaphorin 1; Semaphorins, Class 4; Semaphorin-4; Semaphorin 4;

Wikipedia link : https://en.wikipedia.org/wiki/Semaphorins;

Is substance : O;

Details

Origin ID

D039961;

UMLS CUI

C1136340;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- class 1 semaphorins [MeSH concept]
- class 2 semaphorins [MeSH concept]
- class 3 semaphorins [MeSH concept]
- class 4 semaphorins [MeSH concept]
- class 5 semaphorins [MeSH concept]
- class 6 semaphorins [MeSH concept]
- class 7 semaphorins [MeSH concept]
- class V semaphorins [MeSH concept]
- semaphorins [MeSH concept]
Related MeSH Supplementary Concept(s)
- CD100 antigen [MeSH Supplementary Concept]
- SEMA3B protein, human [MeSH Supplementary Concept]
- SEMA3E protein, human [MeSH Supplementary Concept]
- SEMA4A protein, human [MeSH Supplementary Concept]
- SEMA5A protein, human [MeSH Supplementary Concept]
- SEMA6A protein, human [MeSH Supplementary Concept]
- SEMA6B protein, human [MeSH Supplementary Concept]
- SEMA6C protein, human [MeSH Supplementary Concept]
- SEMA6D protein, human [MeSH Supplementary Concept]
- SEMA7A protein, human [MeSH Supplementary Concept]
- Sema2b protein, Drosophila [MeSH Supplementary Concept]
- Sema3C protein, human [MeSH Supplementary Concept]
- Sema3D protein, human [MeSH Supplementary Concept]
- Sema3D protein, rat [MeSH Supplementary Concept]
- Sema3E protein, zebrafish [MeSH Supplementary Concept]
- Sema3b protein, mouse [MeSH Supplementary Concept]
- Sema3e protein, mouse [MeSH Supplementary Concept]
- Sema4A protein, mouse [MeSH Supplementary Concept]
- Sema4C protein, rat [MeSH Supplementary Concept]
- Sema4c protein, human [MeSH Supplementary Concept]
- Sema4c protein, mouse [MeSH Supplementary Concept]
- Sema4d protein, mouse [MeSH Supplementary Concept]
- Sema4g protein, mouse [MeSH Supplementary Concept]
- Sema5A protein, mouse [MeSH Supplementary Concept]
- Sema5c protein, Drosophila [MeSH Supplementary Concept]
- Sema6A protein, rat [MeSH Supplementary Concept]
- Sema6a protein, mouse [MeSH Supplementary Concept]
- Sema6a protein, zebrafish [MeSH Supplementary Concept]
- Sema6b protein, mouse [MeSH Supplementary Concept]
- Sema6c protein, mouse [MeSH Supplementary Concept]
- Sema6c protein, rat [MeSH Supplementary Concept]
- Sema6d protein, mouse [MeSH Supplementary Concept]
- Sema7a protein, mouse [MeSH Supplementary Concept]
- Sema7a protein, rat [MeSH Supplementary Concept]
- sema 3D protein, mouse [MeSH Supplementary Concept]
- sema3d protein, zebrafish [MeSH Supplementary Concept]
- semaphorin 1a, drosophila [MeSH Supplementary Concept]
- semaphorin 3A lytic peptide [MeSH Supplementary Concept]
- semaphorin 3C protein, mouse [MeSH Supplementary Concept]
- semaphorin 3E, chicken [MeSH Supplementary Concept]
- semaphorin 3G, human [MeSH Supplementary Concept]
- semaphorin 3G, mouse [MeSH Supplementary Concept]
- semaphorin 4B, human [MeSH Supplementary Concept]
- semaphorin 4B, mouse [MeSH Supplementary Concept]
- semaphorin 4E, zebrafish [MeSH Supplementary Concept]
- semaphorin 6D, zebrafish [MeSH Supplementary Concept]
- semaphorin Z8 [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
Validated automatic mappings to BTNT
- Semaphorin-3E [NCIt concept]

Keyword's position in hierarchy(ies) :

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