MeSH definition : Integrin beta chains combine with integrin alpha chains to form heterodimeric cell
surface receptors. Integrins have traditionally been classified into functional groups
based on the identity of one of three beta chains present in the heterodimer. The
beta chain is necessary and sufficient for integrin-dependent signaling. Its short
cytoplasmic tail contains sequences critical for inside-out signaling.;
Integrin beta chains combine with integrin alpha chains to form heterodimeric cell
surface receptors. Integrins have traditionally been classified into functional groups
based on the identity of one of three beta chains present in the heterodimer. The
beta chain is necessary and sufficient for integrin-dependent signaling. Its short
cytoplasmic tail contains sequences critical for inside-out signaling.