pulmonary surfactant-associated protein C

Preferred Label : pulmonary surfactant-associated protein C;

MeSH definition : A pulmonary surfactant associated protein that plays a role in alveolar stability by lowering the surface tension at the air-liquid interface. It is a membrane-bound protein that constitutes 1-2% of the pulmonary surfactant mass. Pulmonary surfactant-associated protein C is one of the most hydrophobic peptides yet isolated and contains an alpha-helical domain with a central poly-valine segment that binds to phospholipid bilayers.;

MeSH synonym : sp-c protein; surfactant polypeptide sp-c; sp-c, surfactant polypeptide; surfactant polypeptide sp c; sp c protein; pulmonary surfactant protein c; pulmonary surfactant-associated protein sp-c; pulmonary surfactant associated protein sp c; pulmonary surfactant associated protein C;

MeSH annotation : DF: SP-C PROTEIN;

Is substance : O;

Details

Origin ID

D037721;

UMLS CUI

C0084242;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Pharmacological action(s)
- pulmonary surfactants [MeSH Descriptor]
Record concept(s)
- pulmonary Surfactant-Associated protein C [MeSH concept]
Related MeSH Supplementary Concept(s)
- CHF5633 [MeSH Supplementary Concept]
- SFTPC protein, human [MeSH Supplementary Concept]
- sftpc protein, mouse [MeSH Supplementary Concept]
- surfactant metabolism dysfunction, pulmonary, 2 [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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