pulmonary surfactant-associated protein A

Preferred Label : pulmonary surfactant-associated protein A;

MeSH definition : An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens, resulting in their opsinization. It also stimulates MACROPHAGES to undergo PHAGOCYTOSIS of microorganisms. Surfactant protein A contains a N-terminal collagen-like domain and a C-terminal lectin domain that are characteristic of members of the collectin family of proteins.;

MeSH synonym : sp a protein; surfactant protein a; sp-a protein; pulmonary surfactant associated protein A;

MeSH annotation : see SCR for species-specific terms; DF: SP-A PROTEIN;

Wikipedia link : https://en.wikipedia.org/wiki/Pulmonary surfactant-associated protein a;

Is substance : O;

Details

Origin ID

D037662;

UMLS CUI

C0143146;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Surfactant protein [MedDRA Preferred Term]
- Surfactant protein A [MedDRA LLT]
Indexing information
- surfactant protein A receptor [MeSH Supplementary Concept]
Pharmacological action(s)
- pulmonary surfactants [MeSH Descriptor]
Record concept(s)
- pulmonary Surfactant-Associated protein A [MeSH concept]
Related MeSH Supplementary Concept(s)
- SFTA2 protein, mouse [MeSH Supplementary Concept]
- SFTPA1 protein, human [MeSH Supplementary Concept]
- SFTPA2 protein, human [MeSH Supplementary Concept]
- SPA4 peptide, human [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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