telomeric repeat binding protein 1

Preferred Label : telomeric repeat binding protein 1;

MeSH definition : A ubiquitously expressed telomere-binding protein that is present at TELOMERES throughout the CELL CYCLE. It is a suppressor of telomere elongation and may be involved in stabilization of telomere length. It is structurally different from TELOMERIC REPEAT BINDING PROTEIN 2 in that it contains acidic N-terminal amino acid residues.;

MeSH synonym : terf1 protein; ttaggg repeat binding factor 1; trf1 protein; TRF1 Proteins; TERF1 Proteins;

Related MeSH term : PIN2 protein; PIN2 Proteins;

Is substance : O;

Details

Origin ID

D035321;

UMLS CUI

C0526985;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- TERF1 Gene [NCIt concept]
- Telomeric Repeat-Binding Factor 1 [NCIt concept]
Indexing information
- TINF2 protein, human [MeSH Supplementary Concept]
- Tinf2 protein, mouse [MeSH Supplementary Concept]
Record concept(s)
- PIN2 protein [MeSH concept]
- telomeric repeat binding protein 1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- TNKS1BP1 protein, human [MeSH Supplementary Concept]
- Tnks1bp1 protein, zebrafish [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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