MeSH definition : Transcription factors that form transcription initiation complexes on DNA, bind to
specific DNA-DIRECTED RNA POLYMERASES and are required to initiate transcription.
Although their binding may be localized to distinct sequence and structural motifs
within the DNA they are considered non-specific with regard to the specific gene being
transcribed.;
MeSH synonym : general transcription factors;
Related MeSH term : general transcription initiation complex proteins;
Wikipedia link : https://en.wikipedia.org/wiki/General transcription factors;
Transcription factors that form transcription initiation complexes on DNA, bind to
specific DNA-DIRECTED RNA POLYMERASES and are required to initiate transcription.
Although their binding may be localized to distinct sequence and structural motifs
within the DNA they are considered non-specific with regard to the specific gene being
transcribed.