" /> DNA gyrase - CISMeF





Preferred Label : DNA gyrase;

MeSH definition : A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Gyrase binds to DNA as a heterotetramer consisting of two A and two B subunits. In the presence of ATP, gyrase is able to convert the relaxed circular DNA duplex into a superhelix. In the absence of ATP, supercoiled DNA is relaxed by DNA gyrase.;

MeSH synonym : DNA-Gyrase;

CISMeF synonym : gyrA gene product; gyrB gene product;

MeSH hyponym : DNA gyrase B subunit; DNA gyrase A subunit; GyrB Protein; GyrA Protein;

Registry Number MeSH : EC 5.99.1.-; EC 5.99.1.3;

Is substance : O;

UNII : EC 5.99.1.3;

Détails


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A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Gyrase binds to DNA as a heterotetramer consisting of two A and two B subunits. In the presence of ATP, gyrase is able to convert the relaxed circular DNA duplex into a superhelix. In the absence of ATP, supercoiled DNA is relaxed by DNA gyrase.

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27/07/2025


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