heterotrimeric GTP-Binding proteins

Preferred Label : heterotrimeric GTP-Binding proteins;

MeSH definition : GTP-BINDING PROTEINS that contain three non-identical subunits. They are found associated with members of the seven transmembrane domain superfamily of G-PROTEIN-COUPLED RECEPTORS. Upon activation the GTP-BINDING PROTEIN ALPHA SUBUNIT of the complex dissociates leaving a dimer of a GTP-BINDING PROTEIN BETA SUBUNIT bound to a GTP-BINDING PROTEIN GAMMA SUBUNIT.;

MeSH synonym : g-proteins, heterotrimeric; gtp-binding proteins, heterotrimeric; heterotrimeric g-proteins; heterotrimeric g proteins; heterotrimeric GTP binding proteins; Heterotrimeric G Protein; G Protein, Heterotrimeric; Protein, Heterotrimeric G; Heterotrimeric G-Protein; G-Protein, Heterotrimeric; Heterotrimeric GTP-Binding Protein; GTP-Binding Protein, Heterotrimeric; Heterotrimeric GTP Binding Protein; Protein, Heterotrimeric GTP-Binding;

CISMeF synonym : EC 3.6.1.46;

Registry Number MeSH : EC 3.6.5.1;

MeSH annotation : GEN or unspecified; prefer specifics; DF: HET G PROTEINS; general or unspecified; prefer specifics;

Is substance : O;

UNII : EC 3.6.5.1;

Details

Origin ID

D020962;

UMLS CUI

C0752348;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Heterotrimeric G Protein [NCIt concept]
- obsolete heterotrimeric G-protein [GO term]
- protein heterotrimerization [GO term]
Indexing information
- GPR35 protein, human [MeSH Supplementary Concept]
- KISS1R protein, human [MeSH Supplementary Concept]
- MCHR1 protein, human [MeSH Supplementary Concept]
- mrgprf protein, rat [MeSH Supplementary Concept]
Record concept(s)
- heterotrimeric GTP-Binding proteins [MeSH concept]
Related MeSH Supplementary Concept(s)
- Bscl2 protein, mouse [MeSH Supplementary Concept]
- G-protein beta3 subunit [MeSH Supplementary Concept]
- GNAT1 protein, human [MeSH Supplementary Concept]
- GNAT3 protein, mouse [MeSH Supplementary Concept]
- GNB3 protein, human [MeSH Supplementary Concept]
- Galpha402 protein, trichomonas vaginalis [MeSH Supplementary Concept]
- Ggamma13 protein, mouse [MeSH Supplementary Concept]
- Gnat1 protein, rat [MeSH Supplementary Concept]
- Gnat2 protein, mouse [MeSH Supplementary Concept]
- Gnb1 protein, mouse [MeSH Supplementary Concept]
- TTC1 protein, human [MeSH Supplementary Concept]
- XLG2 protein, arabidopsis [MeSH Supplementary Concept]
- XLG3 protein, arabidopsis [MeSH Supplementary Concept]
- git5 protein, S pombe [MeSH Supplementary Concept]
- gnb1a protein, zebrafish [MeSH Supplementary Concept]
- guanine nucleotide binding protein (G protein), beta polypeptide 3, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Heterotrimeric G Protein [NCIt concept]

Keyword's position in hierarchy(ies) :

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