Preferred Label : myasthenia gravis, neonatal;
MeSH definition : A disorder of neuromuscular transmission that occurs in a minority of newborns born
to women with myasthenia gravis. Clinical features are usually present at birth or
develop in the first 3 days of life and consist of hypotonia and impaired respiratory,
suck, and swallowing abilities. This condition is associated with the passive transfer
of acetylcholine receptor antibodies through the placenta. In the majority of infants
the myasthenic weakness resolves (i.e., transient neonatal myasthenia gravis) although
this disorder may rarely continue beyond the neonatal period (i.e., persistent neonatal
myasthenia gravis). (From Menkes, Textbook of Child Neurology, 5th ed, p823; Neurology
1997 Jan;48(1):50-4);
MeSH synonym : neonatal myasthenia gravis;
MeSH hyponym : antenatal myasthenia gravis; myasthenia gravis, neonatal, persistent; myasthenia gravis, neonatal, transient; Neonatal Myasthenia Gravis, Persistent; Persistent Neonatal Myasthenia Gravis; Myasthenia Gravis, Persistent, Neonatal; Myasthenia Gravis, Antenatal; Neonatal Myasthenia Gravis, Transient; Transient Neonatal Myasthenia Gravis; Myasthenia Gravis, Transient, Neonatal;
Origin ID : D020941;
UMLS CUI : C0158982;
- Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- DO Cross reference
- Metaterm(s)
- Ne pas confondre avec
- Record concept(s)
- See also (suggested by CISMeF)
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
A disorder of neuromuscular transmission that occurs in a minority of newborns born
to women with myasthenia gravis. Clinical features are usually present at birth or
develop in the first 3 days of life and consist of hypotonia and impaired respiratory,
suck, and swallowing abilities. This condition is associated with the passive transfer
of acetylcholine receptor antibodies through the placenta. In the majority of infants
the myasthenic weakness resolves (i.e., transient neonatal myasthenia gravis) although
this disorder may rarely continue beyond the neonatal period (i.e., persistent neonatal
myasthenia gravis). (From Menkes, Textbook of Child Neurology, 5th ed, p823; Neurology
1997 Jan;48(1):50-4)