MeSH definition : Peptide neurotoxins from the marine fish-hunting snails of the genus CONUS. They contain
13 to 29 amino acids which are strongly basic and are highly cross-linked by disulfide
bonds. There are three types of conotoxins, omega-, alpha-, and mu-. OMEGA-CONOTOXINS
inhibit voltage-activated entry of calcium into the presynaptic membrane and therefore
the release of ACETYLCHOLINE. Alpha-conotoxins inhibit the postsynaptic acetylcholine
receptor. Mu-conotoxins prevent the generation of muscle action potentials. (From
Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed);
MeSH synonym : conotoxin;
MeSH hyponym : alpha-Conotoxins; mu-Conotoxins; mu Conotoxins; mu-Conotoxin; mu Conotoxin; alpha Conotoxins; alpha-Conotoxin; alpha Conotoxin;
MeSH annotation : OMEGA-CONOTOXINS and OMEGA-CONOTOXIN GVIA are available;
Wikipedia link : https://en.wikipedia.org/wiki/Conotoxins;
Peptide neurotoxins from the marine fish-hunting snails of the genus CONUS. They contain
13 to 29 amino acids which are strongly basic and are highly cross-linked by disulfide
bonds. There are three types of conotoxins, omega-, alpha-, and mu-. OMEGA-CONOTOXINS
inhibit voltage-activated entry of calcium into the presynaptic membrane and therefore
the release of ACETYLCHOLINE. Alpha-conotoxins inhibit the postsynaptic acetylcholine
receptor. Mu-conotoxins prevent the generation of muscle action potentials. (From
Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)