cathepsin C - CISMeF

Preferred Label : cathepsin C;

MeSH definition : A papain-like cysteine protease that has specificity for amino terminal dipeptides. The enzyme plays a role in the activation of several pro-inflammatory serine proteases by removal of their aminoterminal inhibitory dipeptides. Genetic mutations that cause loss of cathepsin C activity in humans are associated with PAPILLON-LEFEVRE DISEASE.;

MeSH synonym : dipeptidyl aminopeptidase i; dipeptidyl transferase; Dipeptidyl Peptidase I;

CISMeF synonym : i, dipeptidyl peptidase; transferase, dipeptidyl; c, cathepsin; aminopeptidase i, dipeptidyl; i, dipeptidyl aminopeptidase; peptidase i, dipeptidyl;

Registry Number MeSH : EC 3.4.14.1;

Is substance : O;

UNII : EC 3.4.14.1;

Details

Origin ID

D020789;

UMLS CUI

C0058361;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- cathepsin C [MeSH concept]
Related MeSH Supplementary Concept(s)
- CTSC protein, human [MeSH Supplementary Concept]
- ctsc protein, mouse [MeSH Supplementary Concept]
- ctsc protein, rat [MeSH Supplementary Concept]
See also
- papillon-lefevre disease [MeSH Descriptor]
See also inter- (CISMeF)
- Brensocatib [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Dipeptidyl peptidase I (substance) [SNOMED CT concept]
- dipeptidyl peptidase i [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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