MeSH definition : A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and
modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription
factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active
NF-kappa B to the nucleus.;
MeSH synonym : i kappa b; ikb dna-binding proteins; ikb dna binding proteins; i-kappa b; I kappa B proteins;
A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and
modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription
factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active
NF-kappa B to the nucleus.