caspase 1 - CISMeF

Preferred Label : caspase 1;

MeSH definition : A long pro-domain caspase that has specificity for the precursor form of INTERLEUKIN-1BETA. It plays a role in INFLAMMATION by catalytically converting the inactive forms of CYTOKINES such as interleukin-1beta to their active, secreted form. Caspase 1 is referred as interleukin-1beta converting enzyme and is frequently abbreviated ICE.;

MeSH synonym : caspase, casp1; casp1 caspase; il-1 beta convertase; il1bc enzyme; il 1 beta convertase; converting enzyme, interleukin-1beta; interleukin 1 converting enzyme; beta convertase, il-1; interleukin-1beta converting enzyme; interleukin 1beta converting enzyme; ice protease; convertase, il-1 beta; interleukin-1 converting enzyme; converting enzyme, interleukin-1; il-1 beta-converting enzyme; il 1 beta converting enzyme; beta-converting enzyme, il-1;

MeSH hyponym : Procaspase-1; Procaspase 1; Pro-Caspase-1; Pro Caspase 1;

CISMeF hyponym : EC 3.4.22.-;

MeSH Related Number : Procaspase-1;

Registry Number MeSH : EC 3.4.22.36;

Related CAS MeSH : EC 3.4.22.- (Procaspase-1);

Wikipedia link : https://en.wikipedia.org/wiki/Caspase 1;

Is substance : O;

UNII : EC 3.4.22.36;

Details

Origin ID

D020170;

UMLS CUI

C0534519;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Caspase-1 [NCIt concept]
Indexing information
- CM 269 [MeSH Supplementary Concept]
- EI 2128-1 [MeSH Supplementary Concept]
- N1445 [MeSH Supplementary Concept]
- PD 194035 [MeSH Supplementary Concept]
- VRT 018858 [MeSH Supplementary Concept]
- diphenyl ether sulfonamide [MeSH Supplementary Concept]
Record concept(s)
- Procaspase-1 [MeSH concept]
- caspase 1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- Casp1 protein, mouse [MeSH Supplementary Concept]
Related MeSH term(s)
- caspase inhibitors [MeSH Descriptor]
See also
- Interleukin-1 [MeSH Descriptor]
- apoptosis [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Caspase-1 [NCIt concept]
- Caspase-1 (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients