ryanodine receptor calcium release channel

Preferred Label : ryanodine receptor calcium release channel;

MeSH definition : A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES.;

MeSH synonym : ca release channel-ryanodine receptor; calcium ryanodine receptor complex; receptor complex, calcium-ryanodine; ryanodine receptor; receptor, ryanodine; ca release channel ryanodine receptor; calcium-ryanodine receptor complex; complex, calcium-ryanodine receptor;

MeSH Hyperonym : ryanodine receptors; Receptors, Ryanodine;

MeSH hyponym : ryanodine receptor 3; ryanodine receptor 1; ryanodine receptor 2; Receptor 3, Ryanodine; RyR3; Receptor 1, Ryanodine; RyR1; Receptor 2, Ryanodine; RyR2;

Wikipedia link : https://en.wikipedia.org/wiki/Ryanodine receptor calcium release channel;

Is substance : O;

Details

Origin ID

D019837;

UMLS CUI

C0054493;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Ryanodine receptor [FMA entity]
Indexing information
- 1,1'-diheptyl-4,4'-bipyridinium [MeSH Supplementary Concept]
- NF 307 [MeSH Supplementary Concept]
- anti-ryanodine receptor autoantibody [MeSH Supplementary Concept]
- hadrucalcin protein, hadrurus gertschi [MeSH Supplementary Concept]
Record concept(s)
- ryanodine receptor 1 [MeSH concept]
- ryanodine receptor 2 [MeSH concept]
- ryanodine receptor 3 [MeSH concept]
- ryanodine receptor calcium release channel [MeSH concept]
- ryanodine receptors [MeSH concept]
Related MeSH Supplementary Concept(s)
- RYR1 protein, human [MeSH Supplementary Concept]
- RYR3 protein, human [MeSH Supplementary Concept]
- RyR2 protein, human [MeSH Supplementary Concept]
- RyR2 protein, rat [MeSH Supplementary Concept]
- Ryr1 protein, rat [MeSH Supplementary Concept]
- Unc-68 protein, C elegans [MeSH Supplementary Concept]
- minicore myopathy with external ophthalmoplegia [MeSH Supplementary Concept]
- ryanodine receptor 1, mouse [MeSH Supplementary Concept]
- ryanodine receptor 2. mouse [MeSH Supplementary Concept]
- ryanodine receptor calcium release channel (2460-2495), Ser(2474)- [MeSH Supplementary Concept]
- ryanodine receptor calcium release channel (2460-2495), synthetic [MeSH Supplementary Concept]
Related MeSH term(s)
- calcium channel agonists [MeSH Descriptor]
- calcium channel blockers [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- Ryanodine receptor [FMA entity]

Keyword's position in hierarchy(ies) :

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