disintegrins - CISMeF

Preferred Label : disintegrins;

MeSH definition : A family of polypeptides purified from snake venoms, which contain the arginine-glycine-aspartic acid (RGD) sequence. The RGD tripeptide binds to integrin receptors and thus competitively inhibits normal integrin-ligand interactions. Disintegrins thus block adhesive functions and act as platelet aggregation inhibitors.;

MeSH synonym : Disintegrin;

MeSH annotation : polypeptides from snake venom; platelet aggregation inhib;

Wikipedia link : https://en.wikipedia.org/wiki/Disintegrins;

Is substance : O;

Details

Origin ID

D019483;

UMLS CUI

C0174807;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- ADAM19 protein, human [MeSH Supplementary Concept]
- ADAM23 protein, human [MeSH Supplementary Concept]
- ADAM28 protein, human [MeSH Supplementary Concept]
- ADAM29 protein, human [MeSH Supplementary Concept]
- ADAM30 protein, human [MeSH Supplementary Concept]
- ADAM32 protein, human [MeSH Supplementary Concept]
- ADAM33 protein, human [MeSH Supplementary Concept]
- ADAM3A protein, human [MeSH Supplementary Concept]
- Adam18 protein, mouse [MeSH Supplementary Concept]
- Adam24 protein, mouse [MeSH Supplementary Concept]
- Adam25 protein, mouse [MeSH Supplementary Concept]
- Adam26a protein, mouse [MeSH Supplementary Concept]
- Adam3 protein, mouse [MeSH Supplementary Concept]
- Adam33 protein, mouse [MeSH Supplementary Concept]
- UNC-71 protein, C elegans [MeSH Supplementary Concept]
- agkistrodon venoms [MeSH Supplementary Concept]
- decysin [MeSH Supplementary Concept]
- kistrin [MeSH Supplementary Concept]
Pharmacological action(s)
- platelet aggregation inhibitors [MeSH Descriptor]
Record concept(s)
- disintegrins [MeSH concept]
Related MeSH Supplementary Concept(s)
- DisBa-01, Bothrops alternatus [MeSH Supplementary Concept]
- EC3 protein, echis carinatus [MeSH Supplementary Concept]
- EC6 protein, echis carinatus sochureki [MeSH Supplementary Concept]
- EMF10 protein, eristocophis macmahoni [MeSH Supplementary Concept]
- Fc-saxatilin [MeSH Supplementary Concept]
- KUZ protein, Drosophila [MeSH Supplementary Concept]
- MIG-17 protein, C elegans [MeSH Supplementary Concept]
- accutin [MeSH Supplementary Concept]
- acostatin [MeSH Supplementary Concept]
- acurhagin-C protein, agkistrodon acutus [MeSH Supplementary Concept]
- adinbitor protein, agkistrodon halys brevicaudus stejneger [MeSH Supplementary Concept]
- alternagin-C [MeSH Supplementary Concept]
- bitisgabonin-1 [MeSH Supplementary Concept]
- bitisgabonin-2 [MeSH Supplementary Concept]
- bothrostatin, bothrops jararaca [MeSH Supplementary Concept]
- contortrostatin [MeSH Supplementary Concept]
- cumanastatin 1, crotalus durissus cumanensis [MeSH Supplementary Concept]
- flavorodin [MeSH Supplementary Concept]
- flavostatin [MeSH Supplementary Concept]
- insularin, bothrops insularis [MeSH Supplementary Concept]
- jarastatin [MeSH Supplementary Concept]
- jerdonin [MeSH Supplementary Concept]
- jerdostatin, protobothrops jerdonii [MeSH Supplementary Concept]
- lebestatin protein, Macrovipera lebetina [MeSH Supplementary Concept]
- mojastin protein, crotalus scutulatus [MeSH Supplementary Concept]
- ocellatusin [MeSH Supplementary Concept]
- piscivostatin [MeSH Supplementary Concept]
- saxatilin [MeSH Supplementary Concept]
- stejnin protein, trimeresurus stejnegeri [MeSH Supplementary Concept]
- trimestatin protein, trimeresurus flavoviridis [MeSH Supplementary Concept]
- tzabcanin protein, Crotalus simus tzabcan [MeSH Supplementary Concept]
- ussuristatin 1 protein, gloydius ussuriensis [MeSH Supplementary Concept]
- ussuristatin 2 protein, gloydius ussuriensis [MeSH Supplementary Concept]
- vicrostatin [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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