MeSH definition : A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used
to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE
analog has been reported to augment tumor cell metastatic potential through activation
of protein kinase C. (J Pharmacol Exp Ther 1995; 274(3):1545-51; J Natl Cancer Inst
1994; 86(15):1145-51);
A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used
to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE
analog has been reported to augment tumor cell metastatic potential through activation
of protein kinase C. (J Pharmacol Exp Ther 1995; 274(3):1545-51; J Natl Cancer Inst
1994; 86(15):1145-51)