" /> 12-hydroxy-5,8,10,14-eicosatetraenoic acid - CISMeF





Preferred Label : 12-hydroxy-5,8,10,14-eicosatetraenoic acid;

MeSH definition : A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (J Pharmacol Exp Ther 1995; 274(3):1545-51; J Natl Cancer Inst 1994; 86(15):1145-51);

MeSH synonym : 12-hete;

MeSH hyponym : 12-R-HETE; 12-S-HETE; 12-S-Hydroxyeicosatetraenoic Acid; 12 S Hydroxyeicosatetraenoic Acid; Acid, 12-S-Hydroxyeicosatetraenoic;

Registry Number MeSH : 59985-28-3;

MeSH annotation : DF: note short X ref;

Is substance : O;

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A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (J Pharmacol Exp Ther 1995; 274(3):1545-51; J Natl Cancer Inst 1994; 86(15):1145-51)

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03/05/2025


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