1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine

Preferred Label : 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine;

MeSH definition : A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.;

MeSH synonym : h-7; 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine; h 7;

Wikipedia automatic translation : H7;

MeSH CAS label : piperazine, 1-(5-isoquinolinylsulfonyl)-2-methyl-, (2S-(1(R*(R*)), 2alpha, 3abeta, 7abeta))-;

Registry Number MeSH : 84477-87-2;

MeSH annotation : DF: IQSMP;

Wikipedia link : https://en.wikipedia.org/wiki/H7;

Is substance : O;

Details

Origin ID

D019307;

UMLS CUI

C0044222;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
False automatic mappings
- Arabic numeral 7 (qualifier value) [Inactive SNOMED CT concept]
- GE07 [NCIt concept]
- Serotype H7 (qualifier value) [SNOMED CT concept]
- Seven [NCIt concept]
- WA07 [NCIt concept]
Pharmacological action(s)
- enzyme inhibitors [MeSH Descriptor]
Record concept(s)
- 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1-(1-hydroxy-5-isoquinolinesulfonyl)homopiperazine [MeSH Supplementary Concept]
- 1-(5-isoquinolinesulfonyl)piperazine [MeSH Supplementary Concept]
- 1-(5-isoquinolinylsulfonyl)-3-methylpiperazine [MeSH Supplementary Concept]
- 2-methyl-1-((4-methyl-5-isoquinolinyl)sulfonyl)homopiperazine [MeSH Supplementary Concept]
- FSD-C10 compound [MeSH Supplementary Concept]
- HA 1100 [MeSH Supplementary Concept]
- HMN 1180 [MeSH Supplementary Concept]
- KN 04 [MeSH Supplementary Concept]
- KN 62 [MeSH Supplementary Concept]
- N-methyl-hydroxyfasudil [MeSH Supplementary Concept]
- fasudil [MeSH Supplementary Concept]
- hydroxyfasudil [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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