thapsigargin - CISMeF

Preferred Label : thapsigargin;

MeSH definition : A sesquiterpene lactone found in roots of THAPSIA. It inhibits CA(2 )-TRANSPORTING ATPASE mediated uptake of CALCIUM into SARCOPLASMIC RETICULUM.; A sesquiterpene lactone found in roots of THAPSIA. It inhibits SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES.;

Registry Number MeSH : 67526-95-8;

Is substance : O;

Details

Origin ID

D019284;

UMLS CUI

C0076374;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Thapsigargin [NCIt concept]
Pharmacological action(s)
- enzyme inhibitors [MeSH Descriptor]
Record concept(s)
- thapsigargin [MeSH concept]
Related MeSH Supplementary Concept(s)
- 8-O-(12-(leucinoylamino)dodecanoyl)-8-O-debutanoylthapsigargin [MeSH Supplementary Concept]
- 8-O-(3-(4-aminophenyl)propionyl)-8-O-debutanoylthapsigargin [MeSH Supplementary Concept]
- 8-O-(4-(4-aminophenyl)butanoyl)-8-O-debutanoylthapsigargin [MeSH Supplementary Concept]
- 8-O-(4-aminocinnamoyl)-8-O-debutanoylthapsigargin [MeSH Supplementary Concept]
- L12ADT [MeSH Supplementary Concept]
- dansylthapsigargin [MeSH Supplementary Concept]
- eosinthapsigargin [MeSH Supplementary Concept]
Semantic type(s)
- Biologically Active Substance [UMLS semantic type]
- Hazardous or Poisonous Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Thapsigargin [NCIt concept]

Keyword's position in hierarchy(ies) :

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